SNP Typing and Resequencing
A Snappy System - detecting SNPs with Geniom
Geniom identifies any kind of single nucleotide polymorphism (SNP) in any gene:
- Detect SNPs, deletions or insertions on the same array
- Create arrays for bacterial strain identification and viral subtyping
- Use different probe lengths within the same array for melting point compensation
- Rapidly optimize arrays by fast validation of in silico probes
Stay ahead and use Geniom for random access high-density single nucleotide polymorphism (SNP) genotyping.
The Human Genome Project as well as the characterization of other model organisms has led to the discovery of millions of DNA sequence variants, SNPs being the most common genetic variant. The recent development of high- throughput technologies to simultaneously genotype a multitude of SNPs in a single assay allow for comprehensive studies of complex, multigenic diseases, the detection of genetic variants and comprehensive genotyping of organisms whose DNA sequence data are available. Because of their abundance in the genome and their low mutation rate, SNPs are emerging as new diagnostic markers.
The flexibility of Geniom’s dedicated microarrays enables focused genotyping analyses.
The Geniom technology for mutational and comparative sequence analysis is based on hybridization of sample DNA to specific probes on the custom array. Use genomic sequence information derived from private or public databases, select fully validated sequences from our preselected probe sets to determine design and setup of your array. Supported by the powerful Geniom software, the selection of probes can be adapted to any problem, and arrays can easily be optimized by rapid validation of in silico designed probes.
Expand your possibilities with Geniom.
Genotyping assay oligonucleotides corresponding to specific SNP sequences allow for SNP analysis, resequencing and the detection of deletions or insertions – even on the same array. Fast and reliable screens for mutations with a single base-resolution give rise to multiplex assays, including strain identification of bacteria and subtyping of viruses.